Comparison of antibiotic accumulation in appendix with various methods of its injection

Relevance of the problem: In respect that, lack dynamic morbidity incidence acute appendicitis and frequency postoperative complications, against backdrop increasing number antibiotics. The problem prevention purulent-inflammatory complications during its surgical treatment remains relevant.
 Materials methods: authors compared intensity accumulation ceftriaxone in appendix tissues depending on method injection.
 Results: It turned out that with intramuscular injection 1–2 hours before operation, an amount sufficient to delay growth laboratory culture Escherichia coli is not observed. After intravenous drug, occurs slowly, significantly far behind lymphotropic technique. With ceftriaxone, 1 hour a dose retardant test already fixed, intjection 2 operation – practically corresponds maximum possible, is, action “pure” antibacterial drug.
 Conclusions: selecting antibiotic therapy for introduction by route.
 Bangladesh Journal Medical Science Vol.20(2) 2021 p.268-273